經過多年的研究--發表文章的篇數終於突破五十（這是一個人生的里程--提醒我還需更多的努力）

郭醫師發表論文總覽(~20110911) Publications: (*corresponding author) 1. Ho-Chang Kuo, Kuender D. Yang, Chi-Di Liang, Chin-Nam Bong, Hong-Ren Yu, Lin Wang, Chih-Lu Wang. The relationship of eosinophilia to intavenous immunoglobulin treatment failure in Kawasaki disease. Pediatr Allergy Immunol. 2007;18:354-359. (SCI IF: 2.723). 2. Ho-Chang Kuo, Chih-Lu Wang, Chi-Di Liang, Hong-Ren Yu, Hsin-Hsu Chen, Lin Wang, Kuender D. Yang. Persistent monocytosis after intravenous immunoglobulin therapy correlated with the development of coronary artery lesions in patients with Kawasaki disease. J Microbiol Immunol Infect. 2007;40:395-400. 3. Ho-Chang Kuo, Chih-Lu Wang, Lin Wang, Hong-Ren Yu, Kuender D. Yang. Patient characteristics and intravenous immunoglobulin product may affect eosinophils in Kawasaki disease. Pediatr Allergy Immunol. 2008;19:184-185. (SCI IF: 2.723). 4. Ho-Chang Kuo, Chih-Lu Wang, Chi-Di Liang, Chien-Fu Huang, Hong-Ren Yu, Lin Wang, Kao-Pin Hwang, Kuender D. Yang. The association of lower Eosinophil-related T Helper 2 (Th2) Cytokines with the Coronary Artery Lesions in Kawasaki disease. Pediatr Allergy Immunol 2009;20:266-272. (SCI IF:2.723). 5. Ho-Chang Kuo, Yu-Tsun Wu, Kuender D. Yang, Chih-Lu Wang. New concepts and treatment strategy in Kawasaki disease. Acta Paediatr Taiwan . 2006;47(suppl):7-17. 6. Chih-Lu Wang, Yu-Tsun Wu, Chieh-An Liu, Ho-Chang Kuo, Kuender D. Yang. Kawasaki disease: infection, immunity and genetics. Pediatr Infect Dis J. 2005;24:998-1004. (SCI). 7. Hong-Ren Yu, Rong-Fu Chen, Kuo-Ching Hong, Chin-Nam Bong, Wen-I Lee, Ho-Chang Kuo, Kuender D. Yang. IL-12-independent Th1 polarization in human mononuclear cells infected with varicella-zoster virus. Eur J Immunol. 2005;35:3664-3672. (SCI). 8. Ho-Chang Kuo, Jiunn-Ming Sheen, Kuan-Sheng Wu, Hsiu-Hui Wei, Chih-Cheng Hsiao. Precocious puberty due to human chorionic gonadotropin-secreting pineal tumor. Chang Gung Med J. 2006;29:198-202. 9. Hsin-Hsu Chen, Ho-Chang Kuo, Ling Wang, Hong-Ren Yu, Jiun-Min Shen, Kao-Pin Hwang, Kuender D. Yang. Childhood macrophage activation syndrome different from infection-associated hemophagocytosis syndrome in etiology and outcome in Taiwan . J Microbiol Immunol Infect. 2007;40:265-271. 10. Lin Wang, Rong-Fu Chen, Jien-Wei Liu, Hong-Ren Yu, Ho-Chang Kuo, Kuender D. Yang. Implications of dynamic changes among TNF, membrane TNF receptor and soluble TNF receptor levels in the severity of Dengue infection. Am J Trop Med Hyg. 2007;77:297-302. (SCI). 11. Kuender D. Yang, Chia-Yo Ou, Tei-Yao Hsu, Jen-Chia Chang, Hau Chuang, Chia-An Liu, Hshu-Mei Liang, Ho-Chang Kuo, Ron-Fu Chen and En-Yen Huang. Interaction of maternal atopy, CTLA-4 gene polymorphism and gender on antenatal IgE production. Clin Exp Allergy. 2007;37:680-687. (SCI). 12. Hong-Ren Yu, Ho-Chang Kuo, Jiunn-Ming Sheen, Lin Wang, I-Chun Lin, Chih-Lu Wang, Kuender D. Yang. A unique plasma proteomic profiling with imbalanced fibrinogen cascade in patients with Kawasaki disease. Pediatr Allergy Immunol. 2009;20:699-707. (SCI). 13. Chi-Di Liang, Ho-Chang Kuo, Kuender D. Yang, Chih-Lu Wang, Sheung-Fat Ko . Acquired Coronary Artery Fistula Complicated by Kawasaki disease. American Heart Journal. 2009;157:584-588. (SCI IF:4.357). 14. Hong-Ren Yu, Jiunn-Ming Sheen, Kao-Pin Hwang, Ho-Chang Kuo, Eng-Yen Huang, Yi-Chuan Huang. Typhoid Fever in Southern Taiwan: A Medical Center Experience. Pediatr Neonatol. 2008;49:116-120. 15. Say-Tin Yeap, Jiunn-Ming Sheen, Ho-Chang Kuo, Kao-Pin Hwang, Kuender D. Yang, Hong-Ren Yu. Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus. Pediatr Neonatol. 2008;49:39-42. 16. Ho-Chang Kuo, Chih-Chiang Wu, Tsung-Hsien Yang, Hong-Ren Yu, Chi-Di Liang, Yi-Ju Chen, Kuender D. Yang. Non-Langerhans Cell Histiocytosis in a Child with Kawasaki disease. BMJ Case Reports 2009 [doi:10.1136/bcr.11.2008.1227] 17. Yu-Lin Huang; Meng-Ying Hsieh; Pa-Fan Hsiao; Jiunn-Ming Sheen; Hong-Ren Yu; Ho-Chang Kuo; Sung-Ting Chen; Jing-Long Huang; Kuender D. Yang; Wen-I Lee. Alopecia Areata Universalis After Phenobarbital-Induced Anti-Convulsant Hypersensitivity Syndrome. Immunological Investigations. 2009; 38:383–397. (SCI) 18. Chih-Chiang Wu, Ho-Chang Kuo, Hong-Ren Yu, Lin Wang, and Kuender D. Yang. Association of acute urticaria with Mycoplasma pneumoniae infection in hospitalized children. Ann Allergy Asthma Immunol. 2009;103:134-9. (SCI). 19. Jiunn-Ming Sheen, Ho-Chang Kuo, Hong-Ren Yu, Eng-Yen Huang, Chih-Chiang Wu, and Kuender D. Yang. Prolonged Acquired Neutropenia in Children. Pediatr Blood Cancer. 2009;53:1284-8. (SCI). 20. Kuender D. Yang, Jen-Chieh Chang, Hau Chuang, Hsio-Mei Liang, Ho-Chang Kuo, Yun-Shien Lee, Te-Yao Hsu, Chia-Yu Ou. Gene-gene and gene-environment interactions on IgE production in prenatal stage. Allergy. 2010 Jun 1;65(6):731-9. (SCI IF:6.38) 21. Ho-Chang Kuo, Hong-Ren Yu, Chih-Chiang Wu, Ling-Sai Chang, Kuender D. Yang. Etanercept treatment for children with refractory juvenile idiopathic arthritis. J Microbiol Immunol Infect. 2011 Jan 13;44(1):52-56. (SCI IF: 1.116) 22. Kai-Cheng Lin, Chi-Di Liang, Kuender D. Yang, Hong-Ren Yu, *Ho-Chang Kuo. Monoarticular septic arthritis in a juvenile rheumatoid arthritis patient under etanercept treatment. Rheumatol Int. 2010 Mar 28. [Epub ahead of print] (SCI IF: 1.493) 23. Ho-Chang Kuo, Kudner D. Yang. Update of treatment for Juvenile Rheumatoid Arthritis. Taiwan Medical Journal 2010; 53 (4) : 8-12. 24. Yu-Chen Liu, Chiu-Ping Hou, Chiu-Ming Kuo, Chi-Di Liang, *Ho-Chang Kuo. Atypical Kawasaki Disease- Review of Literature and Clinical Nursing. Hu Li Za Zhi. 2010 Dec;57(6):104-110. 25. Ho-Chang Kuo, Chieh-An Liu, Chia-Yu Ou, Te-Yao Hsu, Chih-Lu Wang, Hsin-Chun Huang, Hau Chuang, Hsiu-Mei Liang, and Kuender D. Yang. Partial protein hydrolyzed infant formula decreased food sensitization but not allergic diseases in a prospective birth cohort study. Int Arch Allergy Immunol. 2011;154(4):310-317. (SCI IF: 2.542) 26. Ho-Chang Kuo, Chi-Di Liang, Chih-Lu Wang, Hong-Ren Yu, Kao-Pin Hwang, Kuender D. Yang. Serum Albumin Level Predicts Initial Intravenous Immunoglobulin Treatment Failure in Kawasaki Disease. Acta Paediatr. 2010;99:1578-1583. (SCI IF: 1.713) 27. Hong-Ren Yu, Chi-Di Liang, Ho-Chang Kuo, Sheung-Fat Ko, Ka-Yin Tsui, Yu-Hsiu Chung, Kao-Pin Hwang, Kuender D. Yang. Air-leak and transient coronary artery dilation in post-infectious bronchiolitis obliterans. Pediatr Int. 2010 Aug;52(4):e221-3. (SCI IF: 0.677) 28. Ho-Chang Kuo, Chieh-An Liu, Chia-Yo Ou, Te-Yao Hsu, Kuender D. Yang. Correlation between atopy and tuberculin/Candida skin test reactivity in a bacillus Calmette-Gue´rin vaccinated cohort. Allergy. 2010 Dec;65(12):1625-6. (SCI IF: 6.38) 29. Ling-Sai Chang, Ho-Chang Kuo, Chieh-Chiang Wu, Hong-Ren Yu, Lin Wang, Hsueh-Wen Chang, Kuender D. Yang. Risk Factors for Mortality of Pediatric Patients without Underlying Diseases. Pediatr Neonatol. 2011 Feb;52(1):34-7. (SCI IF: 0.776) 30. Rong-Fu Chen, Hui-Chen Huang, Chia-Yu Ou, Te-Yao Hsu, Hau Chuang, Jen-Chieh Chang, Lin Wang, Ho-Chang Kuo, Kuender D. Yang. MicroRNA-21 expression in neonatal blood associated with antenatal IgE production and development of allergic rhinitis. Clinical & Experimental Allergy 2010;40:1482-1490. (SCI IF: 4.084) 31. Hong-Ren Yu, Ho-Chang Kuo, Eng-Yen Huang, Chi-Di Liang, Kao-Pin Hwang, I-Chun Lin, Jiunn-Ming Sheen, Tzu-Jou Wang, Chih-Lu Wang and Kuender D. Yang. Plasma Clusterin Levels in Predicting the Occurrence of Coronary Artery Lesions in Patients With Kawasaki Disease. Pediatr Cardiol. 2010 Nov;31(8):1151-6. (SCI IF: 1.151) (Co-1st author) 32. Mindy Ming-Huey Guo, Kuender D. Yang, Hong-Ren Yu, *Ho-Chang Kuo Hypersensitive joint reaction after etanercept treatment in a patient with juvenile rheumatoid arthritis. J Rheumatol. 2011 Mar;38(3):577-9. (SCI IF: 3.854) 33. Hong-Ren Yu, Chen-Kuang Niu, Ho-Chang Kuo, Ka-Yin Tsui, Chih-Chiang Wu, Chien-Hung Ko, Jiunn-Ming Sheen, Eng-Yen Huang, Kuender D. Yang. Comparison of the Global Initiative for Asthma Guideline-based Asthma Control Measure and the Childhood Asthma Control Test in Evaluating Asthma Control in Children. Pediatr Neonatol 2010;51(5):273−278. (SCI IF: 0.776) 34. Ho-Chang Kuo, Chi-Di Liang, Hong-Ren Yu, Chih-Lu Wang, I-Chun Lin, Chia-An Liu, Jen-Chieh Chang, Chiu-Ping Lee, Wei-Chiao Chang, Kuender D. Yang. CTLA-4, position 49 A /G polymorphism associated with coronary artery lesions in Kawasaki disease. J Clin Immunol. 2011 Apr; 31(2):240-4. (SCI IF: 3.583, rank: 38/128, Immunology) 35. Ho-Chang Kuo, Hong-Ren Yu, Suh-Hang Hank Juo, Kuender D. Yang, Yu-Shiuan Wang, Chi-Di Liang, Wei-Chiao Chen, Wei-Pin Chang, Chien-Fu Huang, Chou-Peen Lee, Li-Yan Lin, Yu-Chen Liu, Yuh-Cherng Guo and Wei-Chiao Chang. CASP3 (rs72689236) gene single nucleotide polymorphisms and Kawasaki disease in Taiwanese children. J Hum Genet. 2011 Feb;56(2):161-5. (SCI IF: 2.547) 36. Lee WI, Huang JL, Lin SJ, Yeh KW, Chen LC, Hsieh MY, Huang YC, Kuo HC, Yang KD, Yu HR, Jaing TH, Yang CH. Clinical Aspects and Genetic Analysis of Taiwanese Patients with the Phenotype of Hyper-Immunoglobulin E Recurrent Infection Syndromes (HIES). J Clin Immunol. 2011 Apr;31(2):272-80. (SCI IF: 3.583, rank: 38/128, Immunology) 37. Shu-Ling Kao, Hong-Ren Yu, Ho-Chang Kuo, Ka-Yin Tsui, Chih-Chiang Wu, Ling-Sai Chang, Chi-Di Liang, Yu-Hsiu Chung, and Kuender D. Yang. Higher soluble Fas ligand and transforming growth factor-b levels after omalizumab treatment: A case report. In press “Journal of Microbiology, Immunology and Infection.” (SCI IF: 1.116) 38. Ho-Chang Kuo, Yu-Chen Liu, Chi-Di Liang, Kuender D. Yang. 兒科十大棘手疾病之首--川崎症. Taiwan Medical Journal 2011;54 (2):69-73. 39. Kuo HC, Chiu CC, Chang WC, Sheen JM, Ou CY, Kuo HC, Chen RF, Hsu TY, Chang JC, Hsaio CC, Wang FS, Huang CC, Huang HY, Yang KD. Use of proteomic differential displays to assess functional discrepancies and adjustments of human bone marrow- and Wharton jelly-derived mesenchymal stem cells. J Proteome Res. 2011 Mar 4;10(3):1305-15. (SCI IF: 5.14) 40. Hong-Ren Yu, Hsin-Chun Huang, Ho-Chang Kuo, Jiunn-Ming Sheen, Chia-Yo Ou, Te-Yao Hsu, and Kuender D. Yang. IFN-a production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and independent pathways. Cell Mol Immunol. 2011 Mar;8(2):181-8. (SCI IF:2.765) 41. Lin Wang, Rong-Fu Chen, Jien-Wei Liu, Ing-Kit Lee, Chiu-Ping Lee, Ho-Chang Kuo, Shau-Ku Huang, Kuender D. Yang. DC-SIGN (CD209) Promoter 2336 A /G Polymorphism Is Associated with Dengue Hemorrhagic Fever and Correlated to DC-SIGN Expression and Immune Augmentation. PLoS Negl Trop Dis 5(1): e934. (SCI IF:4.7) 42. Hong-Ren Yu, Ho-Chang Kuo, Hsin-Chun Huang, Li-Tung Huang, You-Lin Tain, Chih-Cheng Chen, Chi-Di Liang, Jiunn-Ming Sheen, I-Chun Lin, Chi-Chiang Wu, Chia-Yu Ou, and Kuender D. Yang. GAPDH is a reliable internal control in western blot analysis of leukocyte subpopulations from children. Analytical Biochemistry. 2011 Jun 1;413(1):24-9. (SCI IF 3.287) (Co-1st author) 43. Wen-I Lee, Jing-Long Huang, Syh-Jae Lin, Kuo-Wei Yeh, Li-Chen Chen, Liang-Shiou Ou, Tsung-Chieh Yao, Meng-Ying Hsieh, Yhu-Chering Huang, Hong-Ren Yu, Ho-Chang Kuo, Kunder D. Yang and Tang-Her Jaing. Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES). Immunobiology. 2011 Aug;216(8):909-17. (SCI IF:3.586) 44. Ho-Chang Kuo, Kuender D. Yang, Suh-Hang Hank Juo, Chi-Di Liang, Wei-Chiao Chen, Yu-Shiuan Wang, Chih-Hung Lee, Edward His, Hong-Ren Yu, Peng-Yeong Woon, I-Chun Lin, Chien-Fu Huang, Daw-Yang Hwang, Chou-Peen Lee, Li-Yan Lin, Wei-Pin Chang, and Wei-Chiao Chang. ITPKC single nucleotide polymorphism (rs28493229) associated with the susceptibility and coronary artery aneurysm formation in Kawasaki disease patients in a Taiwanese population. PLoS One. 2011 Apr 14;6(4):e17370. (SCI IF: 4.351) 45. Ho-Chang Kuo, Ying-Jui Lin, Suh-Hang Hank Juo, Yu-Wen, Hsu, Wei-Chiao Chen, Kuender D. Yang, Chi-Di Liang, Shengyu Yang, Mei-Chyn Chao, Hong-Ren Yu, Shouyan Wang, Li-Yan Lin, and Wei-Chiao Chang. Lack of Association between ORAI1/CRACM1 Gene Polymorphisms and Kawasaki Disease in Taiwanese Children. J Clin Immunol. 2011 Aug;31(4):650-5. (SCI IF: 3.583) 46. Ho-Chang Kuo, Wei-Chiao Chang. Genetic polymorphisms of Kawasaki disease. Acta Pharmacol Sin. 2011 Sep 5. (review article, SCI IF: 1.909) 47. Hong-Ren Yu, Hsing-Chun Kuo, Hsin-Chun Huang, Ho-Chang Kuo, Tai-Yuan Chen, Li-Tung Huang, You-Lin Tain, Chih-Cheng Chen, Jiunn-Ming Sheen, I-Chun Lin, Chia-Yo Ou, Te-Yao Hsu, Yi-Jyun Jheng and Kuender D. Yang. Identification of immunodeficient molecules in neonatal mononuclear cells by proteomic differential displays. Proteomics. 2011 Sep;11(17):3491-500. (SCI IF: 4.426) 48. Ming-Feng Hou, Ho-Chang Kuo, Jih-Heng Li, Yu-Shiuan Wang, Chen-Chia Chang, Ku-Chung Chen, Wei-Chiao Chen, Chien-Chih Chiu, Shengyu Yang and Wei-Chiao Chang. Orai1/CRACM1 Overexpression Suppresses Cell Proliferation via Attenuation of the Store-Operated Calcium Influx-mediated Signalling Pathway in A549 Lung Cancer Cells. Biochim Biophys Acta. 2011 Jul 14. [Epub ahead of print] (SCI IF: 4.66) (Co-1st author) 49. Lee WI, Huang JL, Jaing TH, Shyur SD, Yang KD, Chien YH, Chiang BL, Soong WJ, Chiou SS, Shieh CC, Lin SJ, Yeh KW, Chen LC, Ou LS, Yao TC, Lin TY, Chiu CH, Huang YC, Wu KH, Lin CY, Yu HH, Yang YH, Yu HR, Yen HJ, Hsieh MY, Kuo ML, Hwu WL, Tsai YC, Kuo HC, Lin YL, Shih YF, Chang KW. Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985-2010. Immunobiology. 2011 Jun 21. [Epub ahead of print] (SCI IF: 4.116) 50. Chou YH, Woon PY, Chen WC, Hsu YW, Chang JM, Hwang DY, Chiu YC, Kuo HC, Chang WP, Hou MF, Liu ME, Chang JG, and Chang WC. A Genetic Polymorphism (rs17251221) in the Calcium-Sensing Receptor Gene (CASR) is Associated with Stone Multiplicity in Calcium Nephrolithiasis. PLos ONE 2011 (inpress) (SCI IF: 4.351) 51. Kuo HC, Onouchi Y, Hsu YW, Chen WC, Huang JD, Huang YH, Yang YL, Chao MC, Yu HR Juan YS, Kuo CM, Yang KD, Huang JS and Chang WC. Polymorphisms of Transforming Growth Factor-β Signaling Pathway and Kawasaki Disease in the Taiwanese population. Journal of Human Genetics 2011 (in press) (SCI IF: 2.547) 川崎症相關研究 共18篇 我們希望可以做的更好！ 感恩恩師 楊崑德教授 王志祿醫師 梁啟迪部長 高醫 張老師 及其研究團隊 還有 秋平 及12研的同仁 兒科 所有幫助我的同仁 有你們 才有 川崎症的成果！ 感恩！